Data experts predicts Brighton v Leicester and full Premier League results
Brighton & Hove Albion have a particularly tricky clash this weekend as they take on high-flying Leicester City, who sit above Manchester City with almost a third of the season played.
Graham Potter's men will have to be on top form if they are to take all three points.
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Hide AdFiveThirtyEight use a statistical model to predict Premier League results, and you can check out their verdict on the weekend’s action below:
West Ham v Spurs (Saturday 12:30pm kick-off) - West Ham win (26% chance), Spurs win (51% chance), Draw (22% chance).
Jose Mourinho’s debut in the Spurs dugout will be a highlight of the weekend, and he is backed to claim the win at the London Stadium.
Arsenal v Southampton (Saturday 3pm kick-off) - Arsenal win (61% chance), Southampton win (19% chance), Draw (21% chance).
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Hide AdUnai Emery is tipped for a victory that he desperately needs.
Watford v Burnley (Saturday 3pm kick-off) - Watford win (45% chance), Burnley win (29% chance), Draw (26% chance).
Watford are expected to win as they face former manager Sean Dyche.
Crystal Palace v Liverpool (Saturday 3pm kick-off) - Crystal Palace win (11% chance), Liverpool win (72% chance), Draw (17% chance).